Influence of HIV infection on liver function indexes in Shanxi, China, 2011-2020

Inhalt:
As a dangerous infectious disease, Acquired Immune Deficiency Syndrome (AIDS) often affects multiple organs and systems in AIDS patients. To study the effect of the human immunodeficiency virus (HIV) infection on liver function examinations, we used 142 patients' clinical examination records in a hospital in Shanxi, China. Patient examination records are from October 2011 to November 2020. The study participant applied a Logistic univariate and multivariate regression model to analyze the distribution relationship of liver function indexes between anti-HIV negative and anti-HIV positive. The univariate Logistic regression analysis showed that the differences in albumin (ALB), alkaline phosphatase (ALP), γ-glutamyl transpeptidase (GGT), indirect bilirubin (IBIL), and total protein (TP) between anti-HIV-negative and anti-HIV-positive patients were statistically significant (P<0.2). Using indexes ALB, ALP, GGT, IBIL, and TP for multivariate analysis, the results suggested that ALB, ALP, and TP between anti-HIV-negative and anti-HIV-positive patients were statistically significant (P<0.05). Therefore, when these indicators in the blood are abnormal, HIV antibody screening should be carried out as soon as possible, which is conducive to the early detection of potential AIDS patients.