Identification of new antibiotics using a microfluidic platform
Konferenz: MikroSystemTechnik - KONGRESS 2009
12.10.2009 - 14.10.2009 in Berlin, Germany
Tagungsband: MikroSystemTechnik
Seiten: 4Sprache: EnglischTyp: PDF
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Autoren:
Zang, E.; Martin, K. (Hans-Knöll-Institut, Jena, Germany)
Henkel, T.; Kielpinski, M. (Institut für Photonische Technologien e.V. (IPHT) Jena, Germany)
Wiesmüller, K. H. (EMC microcollections GmbH, Tübingen)
Inhalt:
To overcome the lack of novel antimicrobial substances, we developed a microfluidic platform based on a two-phase segmented flow which enables high-throughput-screening for antibiotic substances. Core of the platform is a new microfluidic chip that allows implementation of two different screening approaches, based on actinomycetes spores and a bead-bound oligopeptide library, respectively.